Protein biomarkers
Target proteins associated with brain-derived vesicles, quantified by calibrated ELISA assays.
VESIBRAIN©
VESIBRAIN analyses biomarkers carried by brain-derived extracellular vesicles in a biofluid sample (e.g. blood, urine, saliva…), bringing biological information into the assessment of brain disorders.
The science
Brain cells continuously release extracellular vesicles — tiny membrane-bound particles that carry proteins and RNA from their cell of origin. Some of them reach biofluids (e.g. blood, urine, saliva…), where they can be isolated and analysed.
Disturbances in how neurons communicate are being studied in depression, anxiety, schizophrenia and bipolar disorder. Brain-derived vesicles offer a window on these processes from a simple biofluid sample (e.g. blood, urine, saliva…).
What VESIBRAIN measures
Target proteins associated with brain-derived vesicles, quantified by calibrated ELISA assays.
Small regulatory RNAs, detected sequence-specifically by a hybridisation immunoassay.
Vesicle enrichment, particle normalisation and quality control from sample to result.
Methodology →How it works
STEP 01
Biofluid samples (e.g. blood, plasma, serum, urine, saliva or CSF) are collected by partners and shipped to our centralised analysis workflow.
STEP 02
Brain-derived biological signals are extracted and analysed: vesicle content such as proteins, RNA, DNA and lipids, profiled at pathway level.
STEP 03
Interpretable, multi-signal results: disease-relevant biological insight, patient stratification and mechanism profiles, with longitudinal tracking when applicable.
STEP 04
Supports diagnosis refinement, informs treatment selection or adjustment, and enables biomarker-driven research and trials.
What changes
Today
→ Delayed clarity
With VESIBRAIN
→ Informed decision
Our approach
Biology does not replace the clinical encounter. VESIBRAIN is designed to complement careful listening and clinical judgement with objective information on underlying neurobiological processes.
An additional, biology-based perspective to support earlier and more personalised assessment.
Biomarker readouts to characterise and stratify patient cohorts.
Companion-test development alongside targeted therapies.
Key terms
A small particle released by cells, enclosed in a membrane and carrying proteins and nucleic acids.
An extracellular vesicle originating from brain cells, enriched from biofluids (e.g. blood, urine, saliva…) for analysis.
A test developed to inform the use of a specific therapy or care pathway.
Clinicians, researchers and partners can contact us to discuss studies, collaborations or access.